About " the problem is vaccinal " 10 big question, it is clear that the expert is solved

Vaccinal, children vaccine. Public opinion blatant.

This burning hot on the weekend, incident of immortal biology vaccine ferments continuously in friend circle.

The first thing that parents do, it is the vaccinal and vaccinal record that goes turning over the child in succession. The germ of their angst is: After all " does manufacturing notes make a holiday " have to vaccinal effect how old influence? How should once is the child vaccinal,this batch of vaccine do? How will choose vaccine henceforth? ...

About vaccine is dispute blame, " life times " interview authoritative expert to answer for a short while doubt dispels doubts, help your reason answer.

Suffer visit an expert

Accessary Beijing bless installs capital medical university Wu Hao of director of hospital infection center

Immunology of college of medicine of Beijing University foundation fastens professor Wang Yuedan

On July 15, bureau of national medicine inspect says, the near future hunts down a batch of production to record the wild dog vaccine that makes a holiday, changchun is immortal the freeze-dry person of finite liability company uses biology science and technology record of existence of hydrophobic vaccinal production builds a holiday to wait to be disobeyed badly " management of drug production quality is normative " behavior.

One is not made the same score, one rises again. Immortal biology issued announcement a few days ago, before Changchun of its company subsidiary grows birthday because of " adsorption does not have a cell 100 white broken combination are vaccinal " (abbreviation " 100 defeat in vain " ) examine not to accord with a regulation, save punishment of administration of medical inspect bureau by Jilin.

On July 22, chief is reported related supervisory management board of national medicines and chemical reagents, via finding out, immortal company fictional production records Changchun and the product examines record, modify craft parameter and equipment at will.

Bureau of national medicine inspect already instructed an enterprise to halt production, call in certificate of GMP of medicines and chemical reagents, the hydrophobic vaccine that recall has not use. Bureau of national medicine inspect already was investigated to company put on record jointly with Jilin province bureau, be suspected of crime move send public security mechanism to investigate criminal duty.

Gate of immortal biology company

In what problem is vaccine of two kinds of problems put respectively?

Director Wu Hao: Not be false vaccine. Many media or from media so called " vaccine makes a holiday " , this concept is inaccurate actually.

At present official bulletin shows the basis, was not itself of wild dog vaccine to give an issue. Manufacturing notes builds holiday and real product to build a holiday to cannot delimit equal-sign.

And " effect price does not accord with a standard " problem, be " bad medicine " problem. The content that is active ingredient actually does not amount to mark, that is to say, vaccine is safe, just effective dose is insufficient, can affect the result of vaccinal have an inoculation.

Current vaccine is to destroy of work or gene project, without live virus or bacterium, the person that won't plant to receiving so causes healthy harm, but if in case vaccinal is the vaccine that effect price does not accord with a standard, the content that also is active ingredient only then does not amount to mark, that is to say, vaccine is safe, just measure insufficient, can affect vaccinal result.

This experience thing is vaccinal, all not be " false vaccine " . Strictly speaking is to belong to " bad medicine " , namely off quality product, and be not false vaccine. Effective vaccine makes false circumstance also eliminate, have a kind of case only, that is in a few out-of-the-way village namely backward perhaps area, put in a few private clinic to buy the phenomenon of false vaccine from illegal channel probably, but this is not the discussion content of this topic.

The technical itself difficulty that vaccine creates is not tall, this can give a few illegal members really with an opportunity given by. Vaccine makes a holiday belong to severe criminal case, belong to put on record of public security mechanism to investigate a category.

Wang Yuedan teachs: Cannot saying its temporarily is " false medicine " . Because be to produce a record to make a holiday, what does very difficult speculation have after all to the product material effect. The branch undertakes appraisal affirms related need.

Vaccine serves as biological product, its security basically is all sorts of undesirable reaction that after show use process is medium or be being used, cause. And vaccinal effectiveness, it is to show its get used to card, usage and the objective that dosage can satisfy precautionary disease below the condition in the regulation.

This second what problem vaccine appears is " effect price is unqualified problem " , individual and character, vaccine of small effect of have an inoculation may be invalid, also may produce effective immune power.

Bureau of national medicine inspect on July 15 announce, supervisory bureau of national provision medicines and chemical reagents begins flight inspection, discover Changchun is immortal freeze-dry person produces existence record to make the conduct such as the holiday with hydrophobic vaccine.

Current, bureau of inspect of Jilin province medicine already called in Changchun is immortal " certificate of GMP of medicines and chemical reagents " , changchun is immortal at the same time the production that already was asked to stop wild dog vaccine.

The 3rd day after this, namely on July 18, jilin saves medical inspect bureau to announce, price of 250 thousand when this company produced in November 2017 100 white broken vaccinal effect is unqualified, press bad medicine processing, amerce 3.44 million.

Occupy supervisory bureau of national provision medicines and chemical reagents additionally the announcement November 3, 2017 shows, two batch 100 white broken vaccinal sampling observation, discover effect price determines the result is unqualified, lot number of product of experience thing vaccine is respectively " Changchun is immortal 100 white broken vaccine of production: 201605014-01; The 100 white broken vaccine that Wuhan biology manufactures: 201607050-2 " .

Children parent or guardian can examine the have an inoculation of 100 white broken vaccine on children vaccinate card to record, with the vaccinal production that announce enterprise and lot number undertake contrasting, judgement is vaccinal of corresponding lot number unqualified 100 white broken vaccine.

In the meantime, also can seek advice from vaccinal unit, by vaccinal unit assistance inquires a have an inoculation the lot number of 100 white broken vaccine, judgement is vaccinal of corresponding lot number unqualified 100 white broken vaccine.

In vaccinal and vaccinal record, tagged vaccinal batch and enterprise

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Director Wu Hao: This should divide a case, I do not advocate fill dozen.

Vaccinal effect price appears problem, it is the problem that prevents effect difference actually. Second liver is for instance vaccinal, actually, antibody appearing after vaccinal second liver is vaccinal is very common.

The experience thing batch that if the child has injected really,bureau of national medicine inspect announces is vaccinal (Changchun is immortal: 201605014-01; Wuhan biology: 201607050-2) , can consider reseed vaccine. But the vaccine of other batch does not have a problem, broaden the scope of batch of experience thing vaccine.

Additional, if the child's parent is second liver patient, that child belongs to second liver to affect tall danger crowd, need affirms to whether second liver antibody produces inside child body, if do not have, be about to fill in time the liver that make second is vaccinal.

Wang Yuedan teachs: Specific whether reseed, again affirmatory otherwise wants new have an inoculation after the expert such as need and conclusion of national mix fish. Vaccinal reseed is put in particular risk, cannot do sth without authorization is blind reseed.

Director Wu Hao: Fill sense of dozen of wild dog vaccine is not great.

The inject period of efficacy of wild dog vaccine is 24 hours, if exceed 24 hours, even if undertakes filling hitting also no point. That is to say, if you are bitten by wild dog, should be in 24 vaccine injects as soon as possible in the hour, want to be before vaccinal become effective only, namely before vaccinal and exciting airframe produces enough immune power, the person has not come on, vaccine can develop effectiveness.

Hydrophobic once come on, its progress rate is very rapid, almost the patient of 100% can die inside 3~5 day. The pet that is bitten without giving thought to is vaccinal too vaccinal, whether does cut bleed, once be bitten hind all need instantly wild dog of have an inoculation is vaccinal.

Nevertheless, hydrophobic have preclinical, it is 3 months commonly in, few number case of illness can be as long as several years. In this paragraph of time, if be bitten person do not have occurrence problem, that need not worry about hydrophobic problem; If appear problem, that not only it is vaccinal, method of a few urgent treatment, had done not have what meaning.

Wang Yuedan teachs: If immune program is at present half-baked, proposal follow-up a few needles change for the other manufacturer, wild dog vaccine that is the same as norms, immunity of the whole journey that finish is vaccinal.

Director Wu Hao: The new life that has liver having second besides directly-related members of one's family -parents beyond, do not need to check antibody commonly.

General and normal medical establishment can detect second liver antibody, each district disease accuses a center to be able to check partial antibody, be like antibody of yaricella, hives. Dan Baibai's broken antibody cannot detect.

Director Wu Hao: Each batches are passed detect strictly.

The vaccine of our country detects those who execute is " batch batch examine " system, detect in the round namely, each batches of products that produce to producing process place are chased batch undertake examining, the qualification that judges every batches of products thereby.

Our country is current from go up to below, it is very strict that superintendency link can say, be aimed at big vaccinal company especially, the possibility that vaccine creates a holiday is almost 0. Vaccine is the product that executes whole technological process to superintend, from former expect production, arrive from the sale carry, from save have an inoculation, each link have strict code and normal flow.

Store vaccinally refrigerate completely in freezer according to the requirement, cold chain is carried. Current, even if is in clinic of one class countryside, also must provide cold chain terminal, our country disease accuses a system to just give deserve to send vaccinal inject license. Vaccinal inject also is finished strictly by the requirement.

Director Wu Hao: Entrance vaccine is not certain better, price of homebred and vaccinal sex is compared taller.

At present the vaccine of homebred vaccine and entrance is not put in apparent difference. Come up strictly tell, no matter the entrance is homebred still, it is certificate of proof just can appear on the market, it is safe and effective. And, look integratedly from function and price, the sexual price of homebred vaccine is compared normally prep above entrance is vaccinal.

Everybody pays close attention to vaccinal problem, itself is understandable, but cannot have one's view of the important overshadowed by the trivial, the vaccine that panicky mood of the public basically is the our country that causes as a result of information asymmetry is no problem on whole, need not cause needless panic because of a few reports.

Wang Yuedan teachs: Do not have blind faith in entrance vaccine.

At present the vaccinal production technology of our country reached international level, homebred vaccine and entrance vaccine difference are not big. Additional, I also do not advocate go to abroad vaccination. Because vaccination needs next undertaking to compare good case in body condition,this is, if go to abroad,journey fatigueds, the likelihood affects vaccinal result.

Wang Yuedan teachs: Not OK.

Make an impertinent figure of speech, this resembles letting the child read same. Vaccination is very important to adult to the child, everybody does not generate panicky sentiment to this.

Director Wu Hao: Cannot because of this vaccinal incident, produce distrust to vaccination.

Achievement of more than 100 years makes clear latter-day medicine, vaccination is the basiccest approach that prevents a disease, no matter be to eliminate smallpox and poliomyelitis, still prevent hydrophobic with tetanus, vaccinal result cannot do not have. Must not give up eating for fear of choking-refrain from doing sth necessary for fear of a slight risk, no matter be a new student groovy vaccine is vaccinal, the wild dog vaccine after passive still content is bitten, tetanic vaccine is vaccinal, it is very necessary.