Recently, academy of advanced technique of Shenzhen of the Chinese Academy of Sciences medicine becomes Laotebai Liu Bin of professor of state-maintaineding college of video like central element group and Singapore cooperates, compose was built close infra-red 2 areas (1000-1700 Nm) collect revulsive glow (AIE) element, precipitate in all through accept rice technical preparation RGD polypeptide target to AIE bougie, realized a head of colloid tumour close infra-red 2 areas are fluorescent / close infra-red element of Guang Shengshuang mode becomes one division picture. I Photoacoustic Imaging Of Orthotopic Brain Tumors of ‐ of II Fluorescence And NIR of ‐ of Emission Dots For Targeted Synergetic NIR of ‐ of Induced of ‐ of research achievement Bright Aggregation (" revulsive glow dot uses bright focusing at former of a cerebral tumor close infra-red 2 areas are fluorescent / close infra-red one Ou Guangsheng cooperates with target is become to the element picture " ) .
Close infra-red 2 areas (NIR-II, 1000~1700 Nm) fluorescence is become resembling is to develop a kind when rise in recent years new-style into like the technology. The visible light with the tradition (400-700 Nm) and close infra-red one area (NIR-I, 700-1000 Nm) fluorescence is become resemble be being compared, photon shows higher penetrable capability, smaller tissue to absorb in NIR-II with scattering. Use NIR-II fluorescence to become can realize Gao Lingmin like the technology (skin rub Er ~ accept rub Er) , high resolution (~ micron class) , super- fast (~ millisecond class) into picture. In ministry of science and technology " 973 " project " the crucial science problem of technology of standard diagnosis and treatment of colloid tumour sperm studies the head " aid financially below, on the Zheng Hairong, Cheng Zonghai and Liu Bin foundation that works in early days (ACS Nano 2017, materials Horizons 2017, advanced Functional Materials 2016, ACS Nano 2014) , be aimed at existing NIR-II fluorescence bougie quanta yield is low (<1% ) , the bottleneck problem that collects revulsive and fluorescent temper by dipping in water to destroy, design preparation of tall quanta yield (6.2% ) NIR-II collects revulsive glow (AIE) bougie, in small rat former a head is colloid on tumour model, implemented high resolution (38 micron) , Gao Xin back is compared (S/N=4.4) NIR-II fluorescence and the NIR-I smooth sound that wear skull cooperate with member of Xiang Shuangmo state becomes target picture, resemble guiding a head to become accurate operation of colloid tumour essence offerred a kind of brand-new method and technology.
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Graph: Close infra-red bougie of 2 areas AIE is used at the head the fluorescence of colloid tumour / mode element becomes Guang Shengshuang picture
