Current, abroad epidemic situation still austere, domestic epidemic situation gets be controllinged effectively. On the choice of vaccine of virus of new coronal of have an inoculation, many peoples encountered " the trouble of the choice " : Should make vaccine? The vaccine that which variety makes is better? How do single shot and double needle choose? To this, reporter of Xinhua News Agency interviewed expert of the authority inside concerned director branch and course of study.
Current, our country already had vaccine of virus of 4 new coronals to add conditional approval to appear on the market via bureau of national medicine inspect. Differentiate by technical course, have two kinds big: It is to destroy live vaccine, 3 when company of the dimension in division of Wuhan company, Beijing is born to promote in Beijing company, traditional Chinese medicine is born in including traditional Chinese medicine produces destroy live vaccine; 2 it is vaccine of gland virus carrier, for Tianjin Kang Xinuo company produces 5 model gland virus carrier is vaccinal.
Which kinds are better?
National Wei Jian appoint concerned director branch expresses, why to no matter use,plant technical course, if the country attachs a condition already formally,approve the vaccine that appear on the market only, its security, validity has fixed number to be propped up according to making, potential profit or foregone income are more than potential risk known perhaps venture, the public can be at ease choose.
The expert inside course of study introduces, the vaccine of new coronal virus of course of two kinds of technologies has distinguishing feature each.
Chinese disease accuses adviser of committee of research and development of vaccine of central researcher, World Health Organization Introduction Shao Yiming, destroy live vaccine is a new coronal virus after education enlarge is added, try to exterminate, next destroy inject of live virus grain arrives in human body, revulsive human body produces immune reaction. Because destroy the meeting when work destroys the albumen antigen of partial virus surface, vaccinal immune former sex is reduced somewhat than live virus, use double needle or the method that 3 needles inject more. First the needle is revulsive memorial cell, inject to react through invoking memory again, come exponential level heightens overall immunity response.
Scientific research tackles key problem group of vaccinal research and development only annals of Wang Jun of academician of squad assistant group leader, Chinese Academy of Engineering introduces, destroy vivid vaccinal and main characteristic is vaccinal composition and natural virus structure more adjacent, immunity is normally respondent stronger also, have good security. This kind of vaccine is stabler, in 2 to 8 Celsius store below movement condition can save for a long time two to 3 years.
And vaccine of gland virus carrier is just like an embarking move " gene of antigen of new coronal virus " the car of goods. Send touch human body cell inside hind, "Gene of antigen of new coronal virus " both neither is met ego is duplicate, also did not extend ill capacity, can convey the albumen antigen that gives new coronal virus however, system of immunity of exciting human body produces antibody.
King army annals introduces, the vaccine of gland virus carrier of our country own research and development is adopted " 5 model gland virus " as carrier, guide " gene of antigen of new coronal virus " , not only can well revulsive counteract antibody generation, still but revulsive enhance cellular immunity. The immune program that approves at present is single shot have an inoculation.
So, how do single shot and double needle choose?
Shao Yiming expresses, to having temporarily or the area of past epidemic disease, awaits without enough time however crowd before urgent task needs, suit vaccine of carrier of virus of gland of inject single shot more.
In addition, vaccine of carrier of virus of single shot gland still has the following profit: It is, single shot have an inoculation finished whole journey immunity namely, because journey is distant,avoided, busy or the job is vaccinal the immunity that deficient does not hit the 2nd needle to cause falls off, guaranteed high vaccinal and vaccinal rate; 2 be, single shot inject is overall cost is inferior, cost effectiveness is compared taller; 3 be, can insufficient circumstance is produced to fall in vaccine of current whole world, single shot is vaccinal but vaccinal pair of times crowd, raised vaccine can reach a gender.
But, one benefit has one disadvantage surely. Shao Yiming hints, the immune reaction intensity with revulsive vaccine of carrier of virus of single shot gland loses commonly at two needles vaccine. Because of this kind of vaccine again when have an inoculation, main generation is aimed at human body " car " -- gland virus carrier, is not " goods " -- " gene of antigen of new coronal virus " memorial reaction. Vaccine of this kind of single shot is in when preventing inchoate popular virus, be no problem, when changing virus of later period mutation, protective efficiency can drop mostly. So, when the choice is vaccinal, want a basis to need to protect the particular case of the crowd, combine the newest monitoring data with local poisonous epidemic, have integrated judgement and science decision-making.
