To prevent all sorts of is short of the happening with ill blood-vessel of head of heart of courage and uprightness, clinical on have a lot of in old people needs to take aspirin for a long time. Recently, anhui dispense with gave the job of an unimaginably queer, hunted down exceed ten million yuan false medicine aspirin! Via detecting, medicaments of this batch of aspirin is special merely " sterling " amylaceous bolus, active ingredient content is 0.
Current, already had chemist's shop of 11 experience case by revoke " business certificate of medicines and chemical reagents " , 29 people are punished by law, medical trade is banned inside 10 years.
More astonishing is, "Amylaceous " aspirin is not be in only Anhui is current, superintendency personnel is demolishing when medical shelter orders two of Harbin holidays that make carry out, shed odd discovery through content, this batch of medicaments still are sent went to 21 province of countrywide 49 areas.
This is meant, still have at present taking not less " aspirin " the patient that help, did not get effective cure at all actually. . . . . .
Well help medicine, became unexpectedly between one evening " the medicine that seize a life " !
Those who disclose this one tremendous an apple of discord is Laozhou of 70 years old, 11 years the head straightens history, need takes aspirin for a long time. But this him the aspirin that from the urban district a drug-store buys, appeared however odd. Because deglutition function is weak, old Zhou Hui puts medicine in the mouth be being contained, chew however gave a sweet taste. . . . . . .
Take the patient of aspirin so for a long time like Laozhou, be absent a few.
Right cardiovascular disease big country
Cardiovascular disease remains the main reason that the whole world dies.
This year January, " Circulation " published American heart association (AHA) heart disease and data of statistic of the epidemiology in soldier show, 17.6 million person died at cardiovascular disease 2016, to 2030 this number will exceed 23.6 million.
About adult of 121.5 million United States contracts the cardiovascular disease of some kind of type. The main reason that coronary heart disease is cardiovascular illness death (43.2% ) , it is soldier next in (16.9% ) .
Be in the United States (2016 data) :
There is 1 person to die at coronary heart disease in every 7 people, every year more than 360 thousand person dies at coronary heart disease; More than 110 thousand person straightens dead at cardiac muscle to death, about every 40 seconds have stem of heart of an American happening; In there is 1 person to die at soldier in every 19 people, every year 140 thousand person dies in soldier, every 40 seconds have 1 in person happening soldier, every 3 minutes of 42 seconds have 1 person to die in soldier.2019AHA heart disease and computation of all of the epidemiology in soldier are occupied
And be in China, from the point of population base, this number is met only much, won't little.
" Chinese cardiovascular disease reported 2017 " show, cardiovascular disease death takes the first place of reason of total death of urban and rural dweller, 10 years cardiovascular disease will suffer from ill number to will still grow quickly henceforth.
Chinese cardiovascular disease has a number now 290 million, in its midbrain soldier 13 million, coronary heart disease 11 million; Cardiovascular disease death takes the first place of reason of total death of urban and rural dweller, the country is 45.01% , the city is 42.62% ; Ill mortality of rural dweller heart and vessels is 298.42/10 10 thousand (heart disease mortality is 144.79/10 10 thousand, cerebral blood-vessel ill mortality is 153.63/10 10 thousand) , ill mortality of townsman heart and vessels is 264.84/10 10 thousand (heart disease mortality is 136.61/10 10 thousand, cerebral blood-vessel ill mortality is 128.23/10 10 thousand) .It is under so austere cardiovascular disease form, regard as all the time help the aspirin that medicine uses, it is the amylaceous bolus of like water off a duck's back unexpectedly, can be imagined if really ever since. . . . . .
So, after all what person should take aspirin?
" fight plaque to treat Chinese expert consensus (2013) " point out, if do not have no-no card, disease of heart and vessels of sex of sclerosis of appearance of congee of all diagnose artery person all should take aspirin to undertake 2 class prevent, include: Coronary heart disease, in be short of soldier of courage and uprightness, outside week is arterial if carotid or lower limbs is arterial narrow ≥ 50% ; Hypertensive amalgamative and chronic kidney is ill person need takes aspirin.
" carry of blood of flesh of understanding of 2018 Europe cardiology rebuilds guideline " point out, treat to intervening via artery of Pi Guan shape (PCI) patient of stability coronary heart disease, aspirin should be used before buy of choose period bracket is entered, accept aspirin therapy to answering before the patient art of anticipate aspirin, and lifelong use fight plaque only drug (it is aspirin normally) cure; To be not ST paragraph the patient that arteries and veins of coronal of drive up acute solicits integratedly, recommend all person that do not have no-no card to take aspirin, 150~300 Mg of initiative bear dosage, maintain dosage for a long time to be daily 75~100 Mg.
In addition, the American cardiology that just rang down the curtain in March learns annual meeting (ACC 2019) , announced disease of newest heart and vessels one class prevents a guideline. Although the position of one class precaution reduces aspirin somewhat, but the guideline still is recommended to 40~70 year old, cardiovascular event risk is higher and the specific adult that does not have factor of haemorrhage Gao Wei, the aspirin that can consider to use small dose (75~100mg of daily profess to convinced) .
One class prevented disease of American heart and vessels 2019 guideline
Take aspirin, what note is there?
Aspirin is fight plaque medicaments classically, through restraining thrombus element A2 (TXA2) the gathering that generation will come to restrain plaque, achieve the effect that reduces thrombosis thereby. Tall danger patient should insist use drug for a long time, crowd of 2 class precaution is lifetime normally the cure that fight bolt.
1.Take small dose, for a long time
Consider to confirm in great quantities, no matter be one class precaution or 2 class precaution, small dose aspirin (50 ～ 100 Mg/d) curative effect and security are optimal. After exceeding afore-mentioned dosage, increase along with dosage, its fight plaque action to did not increase, but harmful response raises instead; And dosage spends a hour, curative effect is not affirmatory.
The lowest that prevents heart disease of sex of coronary artery sclerosis is effective dosage is 75 Mg/d, the lowest that the one class in be short of soldier of courage and uprightness prevents is effective dosage is 50 Mg/d. But, different patient fights the reaction existence difference of plaque medicaments to coequal dosage, special situation but individual change decision dosage, for example extremely senile old people.
2, avoid to he fights thrombus drug or send digestibility ulcer medicine with its operable
Aspirin returns meeting and Buluofen and naphthalene general to be born wait for the body that be not steriod to fight phlogistic drug (NSAIDS) , the haemal attenuant content such as Huafalin and thunder of chloric Bi case (Boliwei) or Sai is chloric, answer to take drug strictly according to doctor's advice.
3, before taking drug or during taking drug, undertake checking, the patient that takes for a long time especially
Because aspirin is had,fight cruor action, take aspirin for a long time to cause hypodermic haemorrhage possibly still, patient expression is the skin purple or have haemorrhage place, have gum haemorrhage or nosebleed even, senile woman particularly common; Take aspirin for a long time to be caused possibly still toxic, make the patient appears have a headache, swimmy, disgusting, vomiting, tinnitus, audition and eyesight drop wait for a symptom.
Because this is during medicine of the kimono before using drug,want to notice to check blood, like red blood cell, plaque, give cruor time, so that be adjusted in time dosage or stop drug.
4, what crowd wants careful use or ban with aspirin?
Aspirin may bring about bowel of gouty recrudesce, asthmatic, stomach the problem such as path injury, haemorrhage, although occurence rate is inferior, but to gouty, asthma and patient of disease of gastric bowel path Ying Shen is used, before using drug, need to go normal medical establishment seeks advice.
The complication of gastric bowel haemorrhage that is precautionary aspirin be caused by, garment of dissolve of optional choose bowel or delay commentate model aspirin, the bring down local and immediate loss to gastric mucous membrane action; Or the medicaments that takes loss of precautionary stomach mucous membrane at the same time, adopt preventive the measure with curb acerbity medicaments and operable protective agent of gastric mucous membrane.
What need reminds is, pregnant woman is pregnant 3 months to be taken orally uses aspirin, can cause fetal growth unusual, later take for a long time, can cause childbirth delay, have the risk of haemorrhage, before reason labors 2 ~ should be banned 3 weeks with. The child cannot take aspirin absolutely! Because can cause serious medicaments harmful response.
Anyhow, to taking the patient of aspirin, should go normal medical establishment buys medicaments.
"Amylaceous " aspirin, still be stay at a respectful distance from sb.
