He lows kind of medicaments be a kind clinical on medicine of the most commonly used the fat that move blood, the key in synthesizing a process through restraining cholesterol is enzymatic, make cholesterol synthesizes suffocate suffocate, reduce serous total cholesterol thereby (TC) , cholesterol of low density lipoprotein (LDL-C) and carry lipoprotein B (Apo B) , still can reduce triglyceride at the same time (TG) , cholesterol of lipoprotein of elevatory high density (HDL-C) . In addition, he lows kind of medicaments still have improvement action of He Kangyan of hemal endodermis function, can prevent sclerosis of arterial congee appearance the formation of spot piece, stable or contractible the spot that already formed piece, prevent and cure spot piece burst, take the occurence rate that can reduce coronary heart disease effectively and mortality for a long time, reduce cardiac muscle to straighten dead to mix significantly the risk with apoplectic head.
We are being done when seeking advice with medicine, often the patient asks about him to low kind of issue that medicaments takes time, most patient knows he lows should take in the late evening, advisory question often is " he lows why to be taken in the late evening, take in other time but with? " this is about to speak of from the synthesis of cholesterol.
Cholesterol itself is not a bastard, it can participate in the synthesis of film of human body cell already, it is vitamin D and the raw material that synthesis of a few hormone needs, the synthesis of cholesterol is a very complex process, the cholesterol that we obtain from inside food, saccharide, amino acid and fatty acid can regard synthesis as the raw material of cholesterol, these raw material are in hydroxide armour the fifth of the ten Heavenly Stem 2 acyl complementary enzymatic A is reductive acid of armour hydroxide the fifth of the ten Heavenly Stem is made below enzymatic catalysis (the body before cholesterol) , this is a step with synthetic the most crucial cholesterol, because of the fifth of the ten Heavenly Stem of this hydroxide armour 2 acyl complementary enzymatic A is reductive enzymatic the key that is synthetic cholesterol is enzymatic, he lows kind of medicaments come through restraining the active with this enzymatic key just about the action of fat of play adjustment blood.
Major cholesterol relies on hepatic synthesis, the hydroxide armour the fifth of the ten Heavenly Stem in liver 2 acyl complementary enzymatic A is reductive enzymatic have sex of law of section of day and night, its active is in noon lowest, and in midnight highest, synthesis of cholesterol at noon is accordingly least, and synthesize in midnight most. Luo Fa is taken before sleeping in the evening he lows, Xin Fa he lows, general cut down he lows, fluorine cut down he lows wait for short effect he lows, just reach consistency of optimal blood drug to the medicaments when midnight, to total cholesterol and cholesterol of low density lipoprotein reduce degree and extent to want apparent excel to give drug in the morning.
But with short effect his lowing photograph is compared, a holds cut down in the palm he lows with lucky easy cut down he lows fall fat active is stronger, half-life is longer, effect time is more protracted. A holds cut down in the palm the half-life that he lows can amount to 14 hours, metabolization child still has very strong fall fat is active, can make A holds cut down in the palm the half-life that he lows is added to 20-30 hour, the half-life that he lows also can reach lucky easy strike 19 hours, accordingly these two kinds no matter still take drug in the morning in the evening,he lows, curative effect and nonsignificant difference, any time in a day are taken all but, and do not suffer dine influence.
Anyhow, luo Fa he lows, Xin Fa he lows, general cut down he lows, fluorine cut down he lows etc before he lows to sleep in the late evening, short effect takes curative effect optimal, and A holds cut down in the palm he lows and lucky easy cut down he lows wait for lasting effect he lows to be taken in time of the random in a day all but. A holds cut down in the palm he lows with lucky easy cut down he lows have very long half-life, leakage is taken not big to curative effect influence, turn day early in the morning is taken can, notice to be taken according to former dosage, do not need to increase dosage. Be in clinical on, control of fat of some patients blood is stabler, cholesterol of low density lipoprotein amounts to mark for a long time, we can suggest these patients are tertian take A to hold cut down in the palm he lows or lucky easy cut down he lows, likewise OK and long-term benefit. @ head healthy @ head head of healthy and allied @ date
