■ Zhang Min of our newspaper reporter
On May 30, the reporter sees in friend circle somebody person sends a message to say: "A lot of hospitals and drugstore do not sell children edition fourth Lin, (this medicine) be be in short supply still retreats city? This to our home this more than for the child that gets acute gastroenteritis, but conscience is necessary medicine, can rely on to break pill only now " .
Release in afore-mentioned messages hind before long, on June 1, national medicines and chemical reagents controls management board (bureau of inspect of medicine of country of the following abbreviation) issue the announcement that proves a file about cancelling 5 medicines and chemical reagents to register approval, involve two children drug, ketone mixes the Duopanli that includes production of limited company of pharmacy of Xi'an Yang Sen among them hang fluid (fourth Lin) , the children bogus Ma Meifen that medicine of a children gives birth to pharmacy limited company by force for Shanghai drips agent (Ai Chang) , these two medicaments all leave a product to give birth to group division by force.
Strong unripe relevant public figure is being accepted " negotiable securities daily " when the reporter is interviewed, express, cancel the active behavior that these two products are an enterprise this. However, according to reporter understanding, regard popular children as medicine, the application of fourth Lin He Aichang ever was oppugned by the outside for many times.
In recent years, bureau of national medicine inspect has been used to the children of many medicines and chemical reagents made afresh edit. "Because medicaments is in hepatic metabolization, excrete in the kidney, children organ development is immature, more incidental also harmful response. Make public information to show, children uses drug harmful response occurence rate is adult double. " look forward to is accepting even plum apothecary " negotiable securities daily " when the reporter is interviewed, express, a few children are put in the excessive, case that surpasses limits to use with medicine. Be aimed at children kind medicaments, the country should be strengthened superintend.
Company response
To cancelling medicines and chemical reagents actively, xi'an Yang Sen and Shanghai are born by force to also be respectively on company official net undertook demonstrative.
Dark official net expresses Xi'an poplar, stop since company this day fourth Lin is produced in chinese mainland and supply. Because the company adjusted Xi'an,making the decision that stops to produce and supply this product is brand-new the manufacturing heart that supplies catenary innovation center. tablet of fourth Lin 10mg still can continue to serve as blame prescription drug and prescription drug to use in China, with Yu Huan solution dyspeptic, abdominal distension, belch, disgusting, vomiting, abdomen bilges painful wait for a symptom.
On June 7, xi'an Yang Sen is in response " negotiable securities daily " when the reporter is interviewed specific introduction cancel this the reason of fourth Lin. Company " in Xi'an brand-new supply total investment of catenary innovation center to be 397 million dollar, predict 2019 second half of the year is enabled. New manufacturing base will establish Chinese medicine to make the new standard of the industry, satisfy the demand that China and market of other Asia-Pacific region increase quickly better. New manufacturing base does not have liquid preparation productivity. After total investment is used, predict annual producible the tablet of the 4 billion unit that pack and capsule, and the breast of 57 million units that pack creams " .
In the meantime, shanghai gives birth to pharmacy limited company by force to release announcement to express, at children bogus stopping since this day Mameifen drips agent (trade name: Ai Chang) produce and supply in chinese mainland. This decision is based on company goal, namely the company will evaluate a product to combine continuously, center resource development and production in order to ensure to be able to satisfy Chinese patient the medicaments of demand of great medical treatment.
Be worth what carry is, these two medicaments are cancelled actively in the enterprise before, also facing the doubt of the market.
Look forward to connects plum apothecary to " negotiable securities daily " reporter introduction, drug group of Ai Chang contains two active ingredient in the portion, it is bogus hemp Huang Jian and right beautiful Sha Fen respectively, this medicines and chemical reagents belongs to medicine of cough of cold of medicine made of two or more ingredients. "Abroad also uses Ai Chang before, but to its 2007 the manual undertook editing. Because abuse, repeat the meeting that use drug to cause undesirable reaction especially. Our country also should be strengthened superintend, to taboo of two years old of the following children this kind of medicaments " .
And fourth Lin is in a few more Euramerican the country has been banned to use or be restricted to use, 2016, website of government of total bureau of supervisory government of national provision medicines and chemical reagents is released " total bureau the announcement that about editing much Pan establishs ketone preparation manual " .
Xi'an Yang Sen to " negotiable securities daily " the reporter expresses, fourth Lin (ketone of much Pan Li) for alternative outside amine D2 suffers Zhouduoba body Jie fights an agent, have stimulative stomach motivation and fight vomitive character, be in at present include Canada, latin america, Africa, Europe and Asia inside 100 many countries and area sell the whole world. since fourth Lin appears on the market in China from 1989, the security that had accumulated nearly 30 years and effectiveness data and about 1 billion person / second use quantity.
Many medicines and chemical reagents are adjusted
Besides besides fourth Lin He Aichang, bureau of national medicine inspect comes this year, undertake editing to the children scope of application of much money medicaments, to some medicaments make known to lower levels " children is banned with " your.
This year on May 29, supervisory management board of national medicines and chemical reagents is released about editing the root of Chinese thorowax injects the announcement of fluid manual, put forward children of this medicines and chemical reagents clearly to ban among them with. And report according to media, it may be said of fluid of inject of the root of Chinese thorowax is the first kind of Chinese traditional medicine injection, use history can appeal consummate century 40 time. Current, the approval article date of fluid of inject of domestic the root of Chinese thorowax has 77 in all.
This year on April 28, bureau of national medicine inspect issues the announcement that joins manual of wheat inject fluid about editing, point out a new student clearly among them, the infant is banned with.
This year on March 9, bureau of national medicine inspect is released " about editing the announcement of manual of many Maude preparation " , the manual that issues according to superintending a branch edits pattern plate, be equal to Duomode's manual will undertake is in more modification, include: "The auxiliary cure that with Yu Man gender or the respiratory tract that have a relapse instead are affected and uric road affects " , "This tasting can use at 3 years old to reach above children and teenage patient. 3 years old of the following children are banned with " ; Etc. Before this, be equal to Duomode's manual applies to all age level.
Before this, "Remove yellow god drug " the use of product of mattress Zhi yellow series also is superintended the branch is adjusted. On August 31, 2016, the country feeds medical inspect total bureau to release Huang Zhu of disuse mattress Zhi to shoot fluid to be used at the new student icteric cure. On August 21, 2017, the country feeds medical inspect total bureau to issue announcement, requirement drug producer takes the manual of preparation to undertake modification to mattress Zhi Huang Kou, made clear this medicine preparation to be able to cause the undesirable reaction such as diarrhoea, vomiting and rash. Ask jalf congealed of lienal empty defecate person careful in order to and proposal dextrose - dehydrogenation of 6- phosphoric acid is enzymatic (G6PD) the person that lack careful with.
One billion two hundred and fifteen million seven hundred and fifty-two thousand one hundred and ninety-two yuan of markets or heavy model
Comprehensive since 2 embryoes policy is carried out, new student quantitative growth is accelerated, children sicken, rate seeing a doctor is in higher level, let children also receive investment market attention with medical market. The research report that negotiable securities of the people's livelihood issues thinks, dimensions of market of drug of children of our country broad sense exceeded 120 billion yuan 2015, predict what will maintain 10% above to add fast.
But a real problem that need faces is, children is in with medical market of the respect such as breed of medical treatment resource, medicines and chemical reagents, amount and the form of a drug or opposite deficient. Look forward to introduces even plum apothecary to the reporter, relatively, children uses medical market very small, because children falls ill rarely, have long-term chronic rarely especially, use dose is very small also. In addition, children is opposite with medicine the form of a drug, taste, carry, store wait to ask to compare tall, manufacturer lacks enough power to have the research and development of children medicine, production and sale.
Additional, look forward to still points out even plum apothecary to a phenomenon is, so called children is centered in cold domain mostly with medicine, and be put in abusive circumstance. "A children catchs a cold one year 67 times to attribute common phenomenon " . Major patulin is raising poison of immune force, disease-resistant, Qing Dynasty to heat up detoxify centrally. "A lot of medicaments just alleviate symptom, cannot prevent illness development. In addition, most cold is OK of self-healing " .
In a series of texts that in Ji Lianmei apothecary releases, besides be equal to Duomode causes the market outside attention, its still announced starch of armour of lienal ammonia peptide, carboxyl the circumstance that the medicaments existence such as sodium abuses. Look forward to still reminds even plum apothecary the society to adenosine of attention A candy is in paediatrics abusive case and the serious and undesirable reaction that produce. "A candy adenosine cannot be used at 14 years old of the following children, chinese traditional medicine injects fluid also should use children eliminate outer " . Look forward to introduces even plum apothecary.
Be worth what carry is, face cure to keep the pressure that charges fee, those who be aimed at medicines and chemical reagents is unreasonable use, superintendency branch also published a series of policy to undertake preventing accusing, include to build eye of the auxiliary monitoring that use drug to wait a moment. Inside course of study the personage looks, of a series of measure carry out, hopeful makes divine medicine exits historical arena.
"Superintendency branch gives off the signal that come to conduce to those who ensure common people use medical security. " Ji Lianmei apothecary thinks.
