After be being removed to stalk of grain more than one year, university of Heibei science and technology announced the findings of incident of paper of Han rain during springtime eventually.
Late on August 31, website of government of university of Heibei science and technology was published " the investigation that the school announces group of Han rain during springtime to remove draft paper and processing result " (next abbreviation " result " ) , say school learning committee establishs board of inquiry, act on " depend on compasses, rigorous standard, be practical and realistic, objective justice lawfully " principle, checked the data of all and primitive test that this paper involves seriously, entrust key laboratory of tripartite state to begin repeat test of test and verify, think the paper that remove draft already had the base that publishs afresh no longer, did not discover group of Han rain during springtime has the subjective case that make a holiday.
" result " say, after the paper is published, pay of individual housing of Han Chunyu, title, pay all did not produce change. In investigating a process, award of the scientific research project that Han Chunyu asks go back is based on institute of the paper that remove draft to obtain actively, performance, honorary title, society holds a post etc. Concerned respect already cancelled the honorary title that Han Chunyu wins according to the regulation, the scientific research project that ended group of Han rain during springtime to assume called in scientific research funds, called in place of group of Han rain during springtime wins award of performance of school scientific research. Individual society holds a post to be being dealt with by legal process.
" result " say, during investigation, han Chunyu and its group cooperate actively, thanks to the attention of scholar of person of the same trade and social community, published the misdirect that causes to express regret to the paper. " result " still express, university of Heibei science and technology grasps hold " start line of business responsible " school example, support and encourage broad teachers and students to explore the people's livelihood of society of scientific and sealed, service. The school will be chance with this, promote scientific spirit further, hold to pair of academic dishonourable behavior " 0 patient " .
Review: "Amaze the people with a single brilliant feat " hind, the experiment cannot be repeated however
Han Chunyu was born 1974, its undergraduate course and Master are read at academy of sciences of agriculture of Heibei Normal University, China early or late, was in China 2003 assist obtain a doctor's degree with medical university, be in along with succeed add assist and be engaged in studying the work. 2006, han Chunyu leaves assist and, get in the university of Heibei science and technology that is located in Shijiazhuang one teachs duty.
On May 2, 2016, the Han Chunyu that does not show in academia reputation before is in as newsletter writer " natural - biology technology " published " NgAgo-gDNA edits a technology for oriented gene " paper. The paper introduced short odd catenary DNA can guide 5 ′ phosphation salt of be addicted to of case family name is cut inside alkaline bacili nucleic acid enzymatic (NgAgo) generation double catenary ruptures, the editor that implements pair of human gene serieses. Sensation is caused after the paper is published, " natural - biology technology " the evaluation says, "It complements likely, replace CRISPR/Cas9 gene to edit a system even " .
Sensation expands very quickly from the academia whole society. By 3 top class scientists of Rao Yi, Lu Bai, chief editor thanking eaves " intellectual " the word to praise and honor of Han Chunyu not stint, say " amaze the people with a single brilliant feat " world of Chinese scientist invention is top-ranking new technology. Subsequently, a large number of reports of media make group of Han rain during springtime becomes Chinese scientist's hot youth learned man, especially its are in " the work that starts a gender is obtained below pallet environment " , be called " phenomenon of Han rain during springtime " .
But very fast, controversy voice comes. In succession the person of the same trade raises doubt to this job of group of Han rain during springtime, experimental hind undertakes in the method that narrates according to institute of paper of Han rain during springtime, they discover NgAgo technology appears and do not undertake gene edits effectively.
This is in academia is not infrequent, a kind of new technology is using initial stage, often lead successfully very low, even because of newly established person the certain details that did not notice and bring about a result to cannot return. But the lab that studies as investment is ceaseless grow in quantity, doubt sound also is in brew ceaselessly, diffuse from academic forum gradually. In July 2016, group of international scientific research phonates publicly on gregarious media, express " the experimental result that cannot see paper of Han rain during springtime is medium " , to avoid resources waste, appeal technology of NgAgo of disuse of scientific research worker.
In October 2016, 13 scientists that come from many top class research organization of domestic phonate publicly on media jointly, express to cannot repeat this test result, the appeal starts academic investigation about the branch. November 2016, domestic and international 20 biologists are in jointly international periodical " protein and cell " on publish academic newsletter, formal the form with academic standard, group of doubt Han rain during springtime of this paper but repeatability.
And publish afore-mentioned papers " natural - biology technology " magazine, also published come from university of Korea head Er, Germany to not the scientist of the research organization such as Lai fort university states use NgAgo cannot detect the incoming letter that compiles the result to gene group. Of paper of group of Han rain during springtime correct the history shows, on November 28, 2016, journal editor puts forward " the editor pays close attention to " , remind scientific research the bound is advertent this paper result " devoid repeatability " anxious.
Did not publish primitive data
Face doubt, respect of Han rain during springtime claims to had repeated for many times, but did not provide the evidence that can offer scientific group evidence. In August 2016, report of Xinhua News Agency says, "To on international a few scientists the requirement announces the requirement of primitive data, university of Heibei science and technology expresses, after a month influences time, han Chunyu will adopt proper form to publish result of test and verify, at the appointed time will authoritative tripartite attest. " but in fact, group of Han rain during springtime did not publish primitive data up to now.
And on September 6, 2016 some home media is opposite in Han Chunyu's special interview, its express " " natural " the magazine has confirmed the experiment can repeat, but still not certain factor affects experimental result " . But subsequently by " natural " magazine field is denied.
While the person of the same trade is oppugned, han Chunyu received many society honor however. On July 13, 2016, han Chunyu is elected to be saved for Heibei division assist vice-chairman, be recommended to be greatly by Heibei division that month " scholar of the Yangtse River rewards a plan " candidate. On August 31, heibei province hair changes appoint give an official agrees to invest big gene of division of Heibei of 224 million yuan of construction to edit a research center. On September 30, university of Heibei science and technology recommends Han Chunyu as " 10 thousand people plan " " in innovation of young science and technology gets a soldier just " .
The Rao Yi with junior guide and support, also not expect this twists and turns. On September 21, 2016, mention in the sends university of Heibei science and technology and president Sun Hexu letter of Rao Yi and arrange of couplet of peak of Shao of academician of Chinese Academy of Sciences, earlier, pass appraise sth through discussion of strict person of the same trade in view of Han Chunyu's job, the international learning periodical that is published in gravity " natural - biology technology " go up, and have no a person of the same trade to see clear problem, according to their academic setting, affirmed Han Chunyu's job according to front of international learning convention. Later, domestic and internationally in succession declare of a lot of scholars cannot use this new technology of Han Chunyu successfully, raise doubt to this job of Han Chunyu, university of science and technology of him rain during springtime giving Han, Heibei and even Chinese biology research brought very big impact, and the obverse side that these doubt did not get coming from Han Chunyu and its group all the time and convincing response. They suggest in the letter each just include discretion of university of Heibei science and technology to treat Han Chunyu to reach its to study positive result.
Additional, mention in the letter, from September first, rao Yi wait for a way to give out inquiry to Sun Hexu of university of Heibei science and technology and president through short message, email namely, but did not win a response.
On October 10, rao Yi letter in reply that gets form of registered letter of side of university of Heibei science and technology, say " the proposal that the school will consider them seriously, the construction that at the same time the hope continues to support college of Heibei science and technology and development " , inscribe date is on September 28. 11 days, rao Yi, Shao Feng decides to publish afore-mentioned two contact letter.
Accepting " daily of science and technology " when interviewing, rao Yi expresses, the reply of university of Heibei science and technology is more general, not clear will have what measure, "Division of Heibei of hope of a lot of people is greatly discussing seriously, is not evade " .
On August 3, 2017, " natural - biology technology " the statement removing draft that issued Han Chunyu group to edit a paper about NgAgo gene. Statement of group of Han rain during springtime is mentioned, cannot regain again according to the experimental program of this paper all the time as a result of scientific research bound a crucial result, "To safeguard the integrality of scientific record, recall our first report " .
" natural - biology technology " the editorial August 3, 2017 introduced in detail from receive doubt to arrive the process that removes draft:
Above all, editorial office asked paper author whether solve why " the result that scientific research bound repeats them hard " . December 2016, group of Han rain during springtime, study a group independently with additionally a few, provided new data, said to had repeated NgAgo gene to edit active. Nevertheless, editor and an exterior evaluation person think " data too too primary " . Accordingly, they decide time of group of Han rain during springtime and more of other research group.
And after already publishing a year many in the paper, afore-mentioned independent research groups " cannot aggrandizement is initiative data " . Accordingly, "After asking for an expert to evaluate feedback opinion of the person, we decide the evidence that the newest data that Han Chunyu and colleague provide can't refute a large number of as initiative as its discovery to be contrary to " . Editorial says, "We believe firmly now, decision of Han Chunyu that remove draft is to defend the best practice that already published scientific research to record integrality " .
It is likewise on August 3, 2017, net of official of university of Heibei science and technology also issues statement, except inform outside removing draft, still say " group of Han rain during springtime agrees to choose laboratory of a tripartite by school arrangement, the test is developed below support of expert of person of the same trade, gene of NgAgo-gDNA of test and verify is editorial effectiveness, announce experimental result, be deeply concerned in order to respond to a society " . School the statement that just provides earlies childhood, already removed draft in view of this paper, the school decides to start pair of Han Chunyu this academic appraise sth through discussion that studies positive result and relevant program.
[reporter] Wang Shikun
[proofread] Yang Yuanyun
[author] Wang Shikun
[origin] group of southern medium signing up for course of study is southern + client end
