Recently, one is published at famous medicine periodical " willow leaf knife " the research that go up causes wide attention. This research is participated in jointly by multilateral scholar, estimate data source through analysing 694 when 1990 ～ come from 195 countries and area between 2016 to drink about individual and crowd, and 592 absorb a risk about alcohol before look up sex and review sexual research, comprehensive systems analysis the alcohol inside global limits is absorbed reach the relation between the disease with death, deformity, this also is what absorb the healthy load that cause about global alcohol up to now is the most comprehensive judge make allowance for to consider. Investigator gave out to the public the safe intake of alcohol -- 0, that is to say, absorb to alcohol, do not have at all " safe " but character.
Small drink happy affection, drink greatly personally. Why to come from " willow leaf knife " research tells us however, no matter intake has many low, want to absorb alcohol only, be insecure? Should study sampling investigation 2016 the whole world male of 49 years old mixes 15 ～ in the female, alcohol is the main risk element that causes disease and premature death, among them female death number is occupied 27.1% , male death number is occupied 18.9% , alcohol causes the death that has close 1/10.
Alcohol is absorbed related to 7 kinds of cancer
The aldehyde that after the alcohol classics that when drinking, absorbs is changed, forms, early Ⅰ be includinged by World Health Organization kind carcinogenic substance, increase the sicken risk of cancer easily. Well-known, a large number of drinking harmful healthy. New Zealand scientist ever published an article to make clear, alcohol is absorbed at least with 7 kinds of cancer come on the risk is elevatory about, included cancer of the liver and esophagus cancer, knot rectum cancer to wait among them.
How is letting us know essence of life of one go with wine above all metabolizing inside body. The process that alcohol recruits in human body metabolization actually very simple, basically rely on two kinds enzymatic: Alcohol dehydrogenation is enzymatic with aldehyde dehydrogenation enzymatic. The alcohol after drinking 5 minutes can enter blood, two hours left and right sides can be metabolized to absorb entirely by human body. After alcohol enters human body, the alcohol dehydrogenation inside body is enzymatic meeting first aldehyde of translate into of little part alcohol, remain much to enter liver, pass aldehyde of hepatic alcohol dehydrogenation enzymatic translate into, rely on aldehyde dehydrogenation again next enzymatic it is aldehyde oxidation with the P450 inside liver second acid, carbon dioxide and water. If aldehyde is done not have by aldehyde dehydrogenation enzymatic change completely, so it can cause hematopoiesis to do cellular DNA damage. If cannot repair DNA injury, criterion this kind of injury will be become permanent, cause immune defect, raise the occurence rate of cancer.
Drink without safe threshold value
Since big drink hurts a body, so small drink happy affection why not OK also?
A year ago, " British medicine magazine " go up to ever published an alignment research, although a week drink 8 ～ 12 cups of beer, also can bring about body of cerebrum sea horse to produce denaturation and atrophy, white simple structure also produces a change, cause loss to the function such as acknowledge, memory thereby. Before half an year, in " natural " there are two heavy pounds to consider to point out early or late on the magazine, the metabolization child aldehyde of alcohol can bring about DNA double catenary to rupture, bring about chromosome recomposition, cause permanent harm of dry cell DNA, the happening that raises a variety of cancer risk.
Publish in by Cantabrigian college student " Liu Xie knife " a research that go up also makes clear, alcohol is absorbed with close because of mortality positive completely, intake is every week the lowest of participator death risk of 100 grams of 0 ～ . Drink to still straighten dead with apoplectic, cardiac muscle the coronary heart disease besides, heart declines, the cardiovascular disease such as tumour maintains aorta of mortality hypertension, mortality positive closes. Big data makes clear, on these diseases, drinking do not have so called safe threshold value. That is to say, want to drink only, disease risk is about prep above those healthy people that do not drink.
In fact, be in early old before Euramerican had done extensive clinical research, the female although every two days drink a cup of red wine, the sicken probability of breast cancer also can increase significantly. In addition, still relevant research makes clear, the alcohol harm to the female relatively the man is older, risk contracting cancer also can have increase accordingly.
" south forefinger of Chinese dweller board " proposal, the alcohol of a day of drinkable wine measures grown man not to exceed 25 grams. However foreign multinomial research makes clear, drink everyday the early-warning line of defence that measured 25 grams to also exceed alcohol. Considering each country crowd fundamental condition is mixed fitness each are not identical, our country still may need to have the clinical investigation and study of big sample book, probably before long meet what redefine health drinks to suit dosage most in the future.
Civil / Wuhan assist with of Wang Wei of hospital poplar Ling
The editor makes: Wang Jianying
