Yesterday, chongqing university releases an information
He Yun of this school pharmaceutical college teachs a group
Realized the world to go up first
To the complete synthesis of element of mildew of wave of 3 kinds of A
This achievement paper
" the complete synthesis of element of mildew of wave of crude production A
And study to the active fighting bacterium of clinical bacterium individual plant "
Be in at 4 days " Nature Communications "
(natural magazine child print) on publish
Among them
δ of element of A wave mildew causes pneumonic bacteria 2 pairs to restrain the effect
About a hundred times better than having antibiotic
On September 5, he Geng teachs Chongqing university pharmaceutical college to coaching in the lab experiment.
The wide application of antibiotic, especially the bacterium that antibiotic abuse brings about is able to bear or endure problem of property of a medicine already became one of difficult problem with clinical most thorny cure, multiple be able to bear or endure medical bacterium even " super bacterium " appear reach spread to already constituted new menace to human health, scientists are developing new-style antibiotic all the time.
The complete synthesis that before He Yun teachs expert of 1000 people plan 6 years, dean of Chongqing university pharmaceutical college, country guided a group to begin element of A wave mildew studies. Introduce according to him, element of A wave mildew (Albomycins) was 1947 a kind of when from inside the metabolization content of mould of edaphic gray catenary depart gets natural child that has the remarkable active that fight bacterium, its structure is comprised by compound of miscellaneous nucleotide of the iron carrier with grow very main to the bacteria and sulfur.
"Because its molecular structure is very complex, difficulty of artificial complex technology is tall, had synthesized successfully without investigator all the time. " Introduction He Yun, they finished second half of the year successfully to be opposite eventually last year δ of element of A wave mildew 1, δ 2 with ε of 3 compound synthesize completely first, had active test respectively, discover its have the different active that fight bacterium severally.
On September 5, he Geng teachs Chongqing university pharmaceutical college to coaching in the lab experiment.
Among them, δ of element of A wave mildew 2 show the admirable active that fight bacterium, element of mildew of the sanded heavenly body of antibiotic annulus third that its are using on market of active and general excel, eternally and penicillin, what get to clinical depart is multiple be able to bear or endure medical bacterium MRSA (be able to bear or endure coccus of grape of yellow of detain oxygen Xi Linjin) also have very good inhibition.
He Yun introduces, they cooperate through hospital of as accessary as Chongqing medical university children, right clinical on of extraction pneumonic streptococcic and multiple be able to bear or endure medical bacterium MRSA has a test, discover δ of element of A wave mildew 2 can kill these bacteria not only, the photograph is hundreds of times lower than other and commonly used antibiotic dosage.
"If A Bo mildew element develops new drug, become treatment likely pneumonic with beat back the specific content of a few super bacterias. " He Yun expresses.
Everybody is looking
