Body of Ms. Wu from a child is strong, fall ill rarely, but after marriage 10 years she is anxious because of the habitual abortion all the time however, even family begins to suspect whether she has done stream of people before marriage.
For this Ms. Wu demands medical service everywhere, however via diagnosing, her habitual abortion is lupus erythematosus be caused by unexpectedly.
Normally gravid inadequacy 28 week, fetal weight are not worth 1000 grams and stop gravid person weigh abortion. And successive 3 or the natural abortion of 3 above is called habitual abortion.
Clinical go up, the habitual abortion patient with inchoate great majority (point to gravid the abortion of 12 weeks of less than happening) reach immunology element to wait with endocrinopathy of genetic element, matrix more about; Terminal habitual abortion (the abortion that points to gravid 12-28 Zhou Fasheng) often mix the mouth inside cervix is flabby, dilatation and curettage or palace neck injury, fetal congenital development the element such as sicken of disagreement of unusual, blood type, matrix is relevant.
Although lupus erythematosus is not the patient fecundity of mobile period insusceptible, but why does lupus erythematosus female abort easily?
1, the illness did not get be controllinged completely
When lupus erythematosus patient the illness has not get control and be been in be pregnant when mobile period, can send accentuation of patient patient's condition, the eclampsia early days such as occurrence albuminuria, hypertensive, oedema is behaved, cause placental blood to offer undesirable, affect fetal blood circulation thereby, cause death of fetal stunt even.
2, amalgamative fight phosphatide to be asked for integratedly
Amalgamative the lupus erythematosus patient that refuses phosphatide to be asked for integratedly is easy form thrombus, applied hormone cure can make blood coagulates high again, can cause miscarriage.
3, placental development undesirable or occurrence disease
Basically pass placenta to carry nutrient material and oxygen fetal, if placental development is undesirable or occurrence disease, fetal cannot get nurture to stop with oxygen to grow character cause miscarriage.
4, amalgamative kidney function is damaged
Lupus erythematosus kidney causes function of kidney of the mother's body to drop, the likelihood affects fetal growth, occurrence abortion, stillborn foetus, stillbirth, cause gravid failure, although loath childbirth is successful, cause not reversible loss possibly also to pregnant woman kidney.
Concerned report points out, 10%-35% is about with deadborn occurence rate inside dead palace of abortion of lupus erythematosus female, embryo. Lupus activity is spent is to add one of with deadborn risk main factors inside dead palace of abortion, embryo.
A Greek research shows, 75% is as high as to control with deadborn occurence rate inside dead palace of the female abortion of serious lupus activity, embryo; Lead with stillbirth inside dead palace of the female abortion that does not have lupus activity, embryo can amount to 14% , and it is only with deadborn rate inside dead palace of normal female abortion, embryo 5% .
Civil / Han Jin (Beijing University hospital of close cloud of the first hospital)
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