Medicaments meets great majority to cause the effect of different level to hepatic meeting, his lowing medicaments is not exceptional also.
He lows to basically act well inside liver. It can restrain liver to change dextrose into cholesterol of low density lipoprotein (LDL-c) function, the effect that move fat is apparent. And one of bases that cholesterol is cellular film, eat him to low in fall cholesterol while, disturb cellular film function easily also.
Accordingly, take him to low easy increase liver cell film appear a gender, make be manacled by cellular film originally the transaminase inside liver cell escapes blood, cause serum transaminase to lift.
because such, many patient concern are long-term he lows kind of medicaments is right hepatic meeting has damage. Actually can need not alarmed, should be only inside reasonable dosage and matter is taken related the attention, his lowing medicine is safe and effective!
Below, "Ask cure " to for you detailed solves this one problem.
What effect does his lowing medicaments have to liver?He lows unusual display is in kind of liver that cause two respects:
It is transaminase lifts but comfortable symptom of all without exception. The medical generation that this is medicaments is kinetic effect, expression is the liver enzymatic level that does not have dependence of semiotic sex, dosage to lift, this and cholesterol reduce itself to concern, its transaminase lifts occurence rate is about 10% . Luo Fa he lows, Xin Fa he lows, A holds cut down in the palm he lows, fluorine cut down he lows to have the case that causes cereal third transaminase to lift, stop drug 2 ～ inside 3 months recoverable normal. 2 it is the liver noxiousness reaction that is put in unwell symptom. This is more infrequent, main show is biliary deposit sex or mixture sex liver to damage, there seldom is acute liver exhaustion to happen below several circumstances.It is current that he lows of all kinds fall the medicaments with best effect of fat of the attune in fat medicaments. Although his lowing medicaments may cause liver loss, but only the small number of people can appear this kind of circumstance, need not worry too.
Whether need to stop drug or adjust dosage, should follow the doctor's advice strictly and remember handling a principle below:
Principle one: Transaminase twice increases ability to require intervention. Become only cereal third transaminase (ALT) , millet straw transaminase (AST) exceed normal upper limit 3 times or flesh acerbity kinase (CK) elevatory exceed normal upper limit 5 times when, just need out of service to he lows and see a doctor to the specialized subject instantly. Of liver cell film appear a gender more sensitive. Besides medicaments, mood how terrible, drink, overworked is excessive, stay up late excessive wait for undesirable lifestyle to also can cause this one problem. Accordingly, in some sense, transaminase lifts is not what important matter, unless be the addition of twice twice.
Under this level, need close observation only its change trend, the ability that has unusually elevatory tendency requires intervention. Take him to low kind of medicaments before, take medical hind to should check 4 weeks hematic fat, liver flesh is enzymatic, enzymatic the function that reach kidney, 3 ～ 6 person that lunar blood fat still did not amount to mark, should adjust him to low kind of medicaments dosage or sort, every 6 ～ after amounting to mark 12 months check.
Principle 2: Take him to low kind during the symptom with occurrence uncomfortable liver, should consult a doctor in time. This is the signal that liver noxiousness reacts normally, the doctor can take step according to different serious level.
The patient doctor that the liver that produces be caused by of his lowing medicaments damages can adopt medicaments to reduce an amount normally or stop medicine to reach protect liver to fall enzymatic benefit bravery the comprehensive treatment that wait, liver function returns to normal in 2-4 Zhou Houke commonly, those who cause serious consequence is very scarce.
What circumstance easy aggravate does the liver that he lows injure?(1) take dosage to exceed bid
Of his lowing medicaments take dosage and liver to damage have affinity. Dose is higher, the probability with unusual transaminase is higher. Initiative when taking, begin from average dose, in invalid or the effect not beautiful and doctor's advice, discretion is abided by to increase dosage below the circumstance that damages without liver.
(2) take period of treatment to grow
The happening of a lot of people for blood-vessel of precautionary heart head, need takes him for a long time to low kind of medicaments. This is the precautionary measures that cannot avoid. If take him for a long time,low kind of medicaments (exceed half an year) person should every 3 months detect liver function.
(3) take other remedy jointly
Using drug jointly is he lows the significant risk element that liver damages kind of medicaments be caused by. This meeting increases hepatic burden greatly, should avoid to use drug jointly, should avoid amino to acetyl phenol, tetracycline especially kind, iodic ketone of chloric pyridine of thunder of chloric Bi case, Sai, amine, blame ketone of Glenn of Nuobeite, music, Zun kind fight the ester inside fungus, big ring kind the combination such as antibiotic is used.
(4) not avoid wine
During taking his lowing medicaments, avoid by all means drinks, drink to also can cause liver function unusual.
