Lung cancer is the our country, chief reason that also is death of whole world cancer. 2015, of our country lung cancer come on and dead example number is amounted to respectively 730 thousand with 610 thousand person, incidence of a disease and mortality are very adjacent. Because clinical diagnostic case of illness already was more,among them reason basically is terminal, lost operation chance. Extreme difference of lung cancer prognosis, research makes clear, 5 years of survival rate of our country lung cancer are only 16.1% .
Accordingly, of lung cancer inchoate diagnose and inchoate cure is to raise lung cancer to live, the important step that drops lung cancer mortality.
Is check-up checks lobar tubercle lung cancer?Will tell normally, clinical go up to have two kinds with the instrument that makes lung cancer sieve check: Bosom X line is checked (the bosom is appeared) with CT. Of two kinds of methods OK fish lung is nodal, but lung cancer returns the tubercle of fish so that pathology diagnoses to affirm, this is hind word.
Nodal cent is lung to mix two malign kinds benignly, among them the move kitchen that malign tubercle just is lung cancer, lymphatic tumour or other cancer likely. According to a of the United States large research, the bosom is appeared and the lung tubercle of CT fish has respectively 96.4% and 94.5% not be cancer.
Does then this specification check no point two kinds?Just is not.
Lung cancer is a kind inchoate with cancer of huge of difference of terminal disease prognosis, the end that becomes lung cancer sieve to check besides discovery cancer, more important is earlier discovery cancer. If one kind checks a method to check to allow, but fish comes is terminal, "Zhu Geliang of after the event " at job of no help; Contrary, a kind of measure is very sensitive, can the lung with very small fish is nodal, even if is accompanying the tubercle that is not cancer in great quantities, but the tubercle that wanting can earlier discovery only is lung cancer, the patient is in likely lung cancer is inchoate be diagnosed to come out.
In fact, the difference that CT and bosom show depends on whether enough delicacy. Be in clinical on, if lung is nodal < 1cm, the doctor may not see as a result fully through the bosom only. On the other hand, the bosom is appeared and the result of CT presents means to have bigger distinction, if tuberculous or bump is blocked at the back of organ and skeleton, going up as a result fully in the bosom also cannot see.
Will tell normally, tubercle is bigger, malign possibility is taller. But this kind of indirect connection is not absolutely, nodular possible also rapid development is terminal lung cancer. Lobar gland cancer is a kind of type of lung cancer, carry blood likely when inchoate focus of a disease is lesser / lymphatic happening move. Once produced far to transfer, disease often cannot operation, "Early " the ground was entered terminal. because such, clinical on terminal patient is namely when diagnose thering is no lack of, prognosis is poorer not fathomless.
So, the sensitivity that CT checks is inchoate lung cancer sifts the requirement that examine.
CT of small dose helix suits lung cancer sieve to check more
Gain ground as what CT checks, economic cost is early not be the element that perplexes doctor and patient. But it is OK that this does not mean CT to check groovy like blood examination is same " groovy " .
CT regards lung cancer sieve as to check a method to must solve have two problems:
CT radiant is accumulated discriminate nodularlyCT radiate is method of this kind of examination inevitable, but also be the negative effect that cannot ignore at the same time. Current, professional video learned the home to go out to reduce a patient to bear below the premise that does not affect video diagnostic quality through fumbling ceaseless research, early the method that radiation measures, namely CT of helix of so called small dose (Low-dose Computed Tomography, LDCT) . The radiate that human body accepts can be accumulated also can follow time elapse subsidise, use CT of small dose helix to be able to let a patient be accepted surely annual examination.
The examination of LDCT can ensure the patient's safety, but another outstanding issue is false positive rate exorbitant. The working cost that makes the doctor is fastened to nodular ancient bronze mirror not only is steep add, still can cause follow-up effect, the waste that if have needlessly,achieves resource of examination, medical treatment and patient angst.
So, how to use LDCT to choose lung cancer patient effectively, the applied itself that compares technical measure even is more important.
Basis " sieve of CT of helix of small dose of Chinese lung cancer consults a directory (2018 edition) " medium commendation, the application of LDCT has a relatively whole system.
Sieve of so called base line is checked those who point to is the LDCT that accepts first. The basis checks likely outcome first, what correspondence gave out in the guideline is politic.
Simple for, if the result is clear, follow-up processing also is clear:
Those who be not lung cancer " spirit way pathological changes " -- the focus of a disease that accepts cure to be not lung cancer, blame to enrage pathological changes " electronegative or nodular " -- next year continue LDCT " lung cancer " -- accept treatmentIf the result is ambiguous, need to introduce more to differentiate method and repeat an examination:
Nodal size clew has a risk (5~8 Mm) , the LDCT after 3 months detects, tubercle is judged to have higher risk all right again after observing nodal change (≥ 15mm) , advanced travel refuses phlogistic treatment, examination of the CT after a month observes nodal change, judge all right againThe situation that subsequently year LDCT examination may encounter and base line inspection are similar.
Handle way through what this kind of flow changes, can accomplish pair of lung cancer as far as possible the sieve with accurate, little side effect examines early, essence of life. If do not have development of technical measure continuity, this is current the most reasonable lung cancer sieve checks an instrument.
Actually, be in early LDCT is already alive 2011 inside bound limits be approbated generally: Sieve of American country lung cancer checks test result to make clear, in tall danger crowd LDCT and traditional bosom check photograph comparing to be able to reduce the lung cancer mortality of 20% fully.
Apparent, after the value that knows this kind of method and meaning, how to become the issue that just is that key.
Bibliographical reference
National Lung Screening Trial Research Team. , aberle DR, adams AM, et Al. Reduced Lung-cancer Mortality With Low-dose Computed Tomographic Screening. N Engl J Med. 2011;365(5):395-409
Sieve of CT of helix of small dose of Chinese lung cancer consults a directory (2018 edition) . Magazine of Chinese lung cancer, 2018(2) .