Times of an ancient name for China (Chinatimes.net.cn) report of Beijing of reporter Jin Wei
Approve because of be being registered again did not allot tardy, zhi Feisheng content (300122.SZ) AC-Hib is triplex and vaccinal face stop production dilemma.
On April 1 evening, a biology of Zhifei of enterprise of vaccine of the first when appear on the market civilian battalion gives out announcement to say, "On November 8, 2018, zhi Fei green bamboo supervises management board to submit the application that AC-Hib vaccine registers again to Beijing food medicines and chemical reagents, up to now, administrative program is still half-baked, the company had be notted receive register again batch. In view of former medicines and chemical reagents period of efficacy of approval article date comes on April 1, 2019, accordingly, subsidiary is in did not obtain register again batch before, the production that suspends AC-Hib vaccine. the production that suspends AC-Hib vaccine..
Suffer effect of arise suddenly declared, company share price was become on April 2 extremely big low, seal quickly drop stop, market prise evaporates more than 8 billion yuan. According to data of annals of Zhi Feisheng content, triplex 2018 vaccinal (AC-Hib) batch sign and issue number to exceed 6 million.
On April 3 evening, biology releases Zhifei outstanding achievement reported 2018, the company achieves business gross earnings 5.228 billion yuan, grow 289.43% compared to the same period; Vest in appears on the market the net gain of company shareholder 1.451 billion yuan, grow 235.75% compared to the same period, every accrual 0.91 yuan. Company 2018 profit allocation beforehand case for 10 cliques extra dividend of 5 yuan of cash (the) that contain tax, so many profit is good, still do not block share price flying have diarrhoea, on April 4, zhi Feisheng content dish in the biggest drop more than 6% , ultimate reply receives 45.69 yuan / , heavy defeat 4.73% .
Have vaccinal trade public figure to " times of an ancient name for China " the reporter expresses, of AC-Hib of Zhi Feisheng content batch did not allot tardy, the likelihood means the significant change of vaccinal production.
Heavy pound vaccine is faced with stop production
Regard domestic vaccine as one of bibcock enterprises of the industry, zhi Feisheng content in recent years all the time with " Bai Ma " attitude appears on 2 class market, with AC-Hib triplex the HPV vaccine of seedling, representative to represent a product, its outstanding achievement is maintaining steady growth.
The announcement of evening said on April 1, on November 8, 2018, green bamboo of subsidiary Zhi Fei supervised management board to submit the application that AC-Hib vaccine registers again to Beijing food medicines and chemical reagents, but up to now, administrative program is still half-baked, have not receive register again batch.
Approve to receiving AC-Hib vaccine to be registered again influence, zhi Feisheng content indicates in announcement, if this product obtains annotate on book no longer, will reach the management outstanding achievement henceforth to produce bigger effect 2019 to the company.
Dong Bi of Zhi Feisheng content is in a personage to accept " times of an ancient name for China " when the reporter is interviewed, say, company the first time application was 2014, a period of efficacy of batch of article is 5 years, arrived that is to say 2019, batch civil expire need applies for again, cancelling this basically is time problem, as to did not acquire batch of article, we did not receive an announcement or explain. "At present the company still has stock, do not affect the sale that already produced a product. Do not affect the sale that already produced a product..
Data of net of official of Zhi Feisheng content shows, AC-Hib vaccine basically is used at preventing A group, C group the infection sex disease that bloodsucking bacili causes meningitis coccus and B flu, if cerebral backbone meningitis, pneumonic, septicemia, epiglottis is phlogistic,wait. As we have learned, this vaccine can replace AC group vaccine drifting a head and Hib vaccine, reduce vaccinal anguish for many times, applicable object is in Feburary age reach above children.
According to annals exposure, the company shares 5 kinds of own products at present making work, include exclusive AC-Hib triplex and vaccinal, ACYW135 sheds cerebral polysaccharide vaccine, Hib vaccine, AC to shed cerebral polysaccharide to combine vaccinal, small card, 6 kinds act as agent or consultative promotion product is making work, vaccine of the vaccine of 4 price HPV that includes silent Sha Dong, 9 price HPV, 5 price annulus shape vaccine and 23 price are pneumonic, destroy vivid armour liver is vaccinal, and Zhejiang general health armour liver decreases poisonous live vaccine.
Among them, AC-Hib vaccine is the company is approved sign and issue the vaccinal product with the largest amount, triplex 2018 vaccinal (AC-Hib) batch sign and issue number to be 6436805, grow 36% compared to the same period. Current, AC-Hib vaccine is main by subsidiary green bamboo produces Zhi Fei, annals shows, the business income that green bamboo contributes Zhi Fei is 1.24 billion yuan; Net profit is 530 million yuan, occupy than 3 into.
Zhi Feisheng matter says to already had now sufficient about 6 million product, can satisfy annual sold demand 2019. But if stop production, still can be opposite the outstanding achievement of the parent company brings concussion, be based on this just about, cause the attention of capital market and broad shareholder.
Vaccine superintends hasten to father
Current, biology has not announce Zhifei to did not win the account that approves again. " times of an ancient name for China " the reporter is in a personage to seek testimony to Dong Bi at this point, the other side says superintendency branch also did not give a specific reason.
Vaccinal trade public figure expresses, this and whole now vaccine are superintended, include to register appear on the market etc be in concern from strict state. 2018, incident of vaccine of immortal biologic problem also is forcing vaccinal industry superintends reform.
Current, our country is managing separate legislation to vaccine.
Media cite is close to personage of bureau of national medicine inspect to express, "Generally speaking, problem of occurrence security of medicines and chemical reagents, effectiveness, can be washed out, but vaccinal if if manufacture technology,lagging behind only, may be washed out. May be washed out..
This Zhi Feisheng content continues to was not obtained batch, likelihood and vaccinal craft are concerned. According to " Chinese negotiable securities signs up for " analyst of industry of medicine of restful negotiable securities says cite, before this " AC-Hib " triplex the seedling is all the time with " liquid " configuration appears on the market sale, and vaccine of liquid of requirement of near future state needs purify assist dose, instead " solid " freeze-dry pink configuration, accordingly, "AC-Hib " vaccinal former recipe needs to undertake revise and appearing in the newspaper afresh.
Vaccinal trade public figure expresses, agent of assistant of of all kinds aluminium applies extensively at the mankind and animal vaccine preparation, basically be agent of this kind of assistant can enhance immune result, but also can have harmful response rate. "In recent years, the metallic aluminium that place of aluminous assistant agent contains is neurological to the mankind may influential and be taken seriously domestic and internationally.
In fact, in August 2018, careful of medicines and chemical reagents of supervisory management board of national medicines and chemical reagents judges a center to release about " precaution uses agent of vaccinal aluminium assistant instructor principle " seek an opinion, basically be aimed at problem of aluminous assistant agent namely. The opinion says, the critical process parameter that affects preparation of aluminous assistant agent should be made clear before appearing on the market, sufficient manufacturing process is built to control strategy on this foundation, include performance data of key and control of parameter of main technology operation, semifinished product to detect etc.
" times of an ancient name for China " the reporter seeks testimony to Zhi Feisheng content at this point, the other side expresses, the AC-Hib vaccine that at present the market supplies is the craft previously, craft respect did not change, when applying for afresh, also did not change.
Be worth what carry is, the another fist product of Zhi Feisheng content is the HPV vaccine of company of Sha Dong of silent of acting United States, this vaccine is heated up to fry by the market recently, many local stitch are begged hard. According to Zhi Feisheng content annals discloses, on November 5, 2018, company and company of silent Sha Dong agreed with respect to vaccine of HPV of 4 price, 9 price come from January 1, 2019 about eighteen billion and two million yuan product base purchase adds up to during June 30, 2021.
Before this, chinese mainland area still does not have the official sale of vaccine of 9 price HPV, of this product appear on the market the blank with 9 valence vaccinal HPV of home of sale general fill. Vaccinal trade public figure discloses, the profit of vaccine of 9 price HPV is very huge.
