Recently, inferior fly (Shanghai) Affinity of limited company of biology medicine science and technology (Shanghai) (next abbreviation " affinity " ) the Pre-A that finishs RMB of 6 ten million annulus financing. This round of financing is gotten by capital of huge rock continuous heavy rain cast, teng Yuan investment follows cast.
Affinity is home's banner tumor small environment is answered model platform of medicaments research and development. The group uses certain protein enzymatic the characteristic that organizes particularity tall expression in tumor, the medicaments that development activations in tumor small environment is transmissive system, through be being transformed to the design of medicaments, make its are activationed by particularity in tumor organization, reduce its systematization noxiousness thereby, widen its treat the window.
Raise medicaments target to be mixed to particularity the important principle that constituent particularity is medicaments development, it is for instance in tumor immunity cure and associated therapy, although the depressor of immune check check the number of such as PD-1/PD-L1 antibody, CTLA-4 antibody is clinical curative effect is outstanding, but undesirable incident is observed related more serious immunity, accordingly, the noxiousness that reduces the overlay after medicaments couplet is used becomes promotion to treat a key of the effect jointly.
Here setting falls, the remedy that uses activation of tumor small environment is transmissive system, can transform development to have immunity to treat foreground jointly and the medicaments that remedial window is restricted by noxiousness, this is one of efficient ways that raise tumor to treat the effect, market prospect is capacious.
Regard the technology inside this domain as lead company, affinity group studies for a long time deep mechanism, practice is seasoned, the achievement of medicaments research and development that is based on activation of tumor small environment is in world banner level, transform in compound, clinical before of research after fumbling for a long time, first product of platform already was obtained batch enter clinical trial.
Li Yuhui of virgin officer partner is opposite capital of huge rock continuous heavy rain this expresses: "The new drug research and development that is aimed at tumor is the direction that the key of capital of huge rock continuous heavy rain pays close attention to all the time, affinity is driving medicaments to develop from 1 enter 2 phase. In the meantime, affinity is based on its technology advantage, limitation of noxiousness of systematization of clear, existence treats first choice curative effect the window and the remedy that has synergism with PD-1 undertakes transforming, the strategy of new drug research and development of this differentia dissimilation makes affinity precedes continuously. The company will be in next first product is evaluated in clinical trial, the technology that expects a company can be in as soon as possible clinical on show its potential, offer new remedial alternative for the patient, benefit whole world. Benefit whole world..
Doctor of time of company father Liu is immunology and the expert that medicaments designs relevant domain, have research of nearly 20 years to this core mechanism, the understanding that having scientificly to life is deep. Regard research and development of affinity technology product as leader, does Liu Chen express: ? Gather up of ⒐ of crab of americium of ┪ of bursa of busy of green of Ge of of a surname of of antrum of compose narrow κ uses up exhausted of bail of the blade of a sword of ┪ of Kou of quiet of of ü of instruct of pod of 9 bureau to fizzle out spell mace of gallopping ┪ mu б of Pu of arrest bath ⒘ makes an appointment with white Yong to do not have the bend so as to breakstubborn austral frequency is exhausted. Gather up of ⒐ of crab of americium of ┪ of bursa of busy of green of Ge of of a surname of of antrum of compose narrow κ uses up exhausted of bail of the blade of a sword of ┪ of Kou of quiet of of ü of instruct of pod of 9 bureau to fizzle out spell mace of gallopping ┪ mu б of Pu of arrest bath ⒘ makes an appointment with white Yong to do not have the bend so as to breakstubborn austral frequency is exhausted..