Respecting " crowd of lung cancer tall danger " , what we think of first most commonly is smoking, get on in years, male. But the research conclusion of in quick succession and clinical phenomenon clew, we may want break this one inherent understanding.
Before two days, I see one is published in " magazine of new england medicine " the new research that go up, those who say is: Academy of national cancer of American cancer institute and United States considers to discover, 1995~2014 year, in patient of lung cancer of American new hair, female incidence of a disease is in 30~49 year old age Duan Jing exceeded the male like that, and smoking element can not explain this phenomenon completely.
Not long ago, chen Haiquan of accessary tumour hospital teachs Fudan University group, the research that in area of Shanghai Min travel 7 community begin also discovers, female, do not smoke the crowd becomes crowd of tall danger of Chinese lung cancer gradually. Specific for, in the crowd of eleven thousand three hundred tall danger that sifts fish, rate of sicken of male and female is 168/10 respectively 10 thousand with 358/10 10 thousand; Smoking, do not smoke crowd sicken rate is 159/10 respectively 10 thousand with 337/10 10 thousand.
Friend of my a doctor is in Beijing some famous tumour hospital made diagnosis and treatment of old lung cancer. He says, in the outpatient service that comes nearly 5 years, do not smoke the person that the female sees a doctor is really apparent grow in quantity. He also asked them expert of epidemiology of hospital lung cancer, everybody says not to smoke number of patient of female lung cancer rises somewhat really.
Without doubt, smoking is the immediate risk element of lung cancer, too much research confirmed this is nodded, but smoking is not the only reason that causes lung cancer however. Although still do not have exact wording at present specific explanation " why lung cancer searchs not to smoke female " , but from theoretic speculation, concern with a few elements probably.
1. passivity smokes. Although oneself do not smoke, but a lot of females live for long in secondhand in smoke or environment of 3 hands smoke. The harm of passive smoking may compare active smoking bigger.
2. environment is polluted. Make " PM2.5 causes lung cancer certainly " conclusion is vogue early, but up to now research already can confirm, air pollution and lung cancer have dependency.
3. kitchen lampblack. Somebody thinks, cannot eliminate the contribution that kitchen lampblack leads to sicken of female lung cancer. But also have an expert not so think, reason is: Young do not smoke in patient of female lung cancer, majority does not stir-fry cook.
4. pressure is too great. Social development lets professional female assume a more families and actuating pressure, high pressure may weaken immune function, increase risk contracting cancer.
5. hormone is affected. A few females are to be in gravid or after be pregnant, diagnose suffer from on of lung cancer, body hormone change comes on with lung cancer probably have dependency. We know, breast cancer and hormone change are concerned, and a few lung cancer and breast cancer are having collective gene change.
Did not smoke to get lung cancer however, let a person be accepted hard really, but this is reality. All cancer are a variety of elements the result of joint action, internal cause, external cause, luck is influencing factor.
Nevertheless, mass data shows, do not smoke woman place suffers from lung cancer to be gland cancer more, especially alveolar cancer; And smoking male suffers from those who go up with in the center of model lobar scale cancer is given priority to. Former and general cause by petty grain, those who invade is lung brim place, if differentiation pitch is good, remedial effect is opposite better. Gene of half existence EGFR is made an appointment with to mutate in gland cancer, if cancer of this kind of gland uses corresponding target to medicaments, curative effect is pretty good. And in the center of smoking brings about model lobar scale cancer, corresponding target to medicaments little, remedial difficulty is greater.
