■ Tang Feng of our newspaper reporter
Recently, college of medicine of university of American haing Buddha reachs his hospital of woman of Mu of the case in accessary orgnaization cloth all suggests cancel 31 papers of a famous researcher, because they are included " those who distort and / or bogus data " . " science " the magazine calls his one of scientific and con cases with the most notorious this century.
Ceng Sheng of cardiology home Piero Anversa said to discover in the heart can the dry cell of second birth cardiac muscle. But 2014, other research group expresses that he cannot repeat the result of Anversa, college of medicine of haing Buddha university started relevant investigation, and cancel firstly piece paper. 2015, anversa lab is shut.
This, investigation orgnaization was not announced have problem paper list, but expressed to had informed relevant periodical in a statement.
Drink praise the whole world
Be in early 2001, anversa research group says, can do a cell with marrow (C-kit) make cardiac muscle second birth. Relevant paper is published at " natural " magazine. Academy of national sanitation of Anversa and United States (NIH) the group of a research that Donald Orlic heads goes to C-kit infuse inside the mice heart that contracts heart disease, these cells are changed successfully inside 9 days become cardiac muscle.
2003, the person such as Anversa is in again " cell " magazine dispatch says not to need medullary dry cell, the heart of use maturity does a cell can repair cardiac muscle. Anversa still checked those at the heart of heart disease patient dying, the muscle that discovers organ of wh some of which is OK reborn.
These theory challenged a tradition, shook whole academia for a short while, people begins to do cellular infuse therapeutics to hold to the heart expect strongly. Anversa also is considered as the inaugurator of domain of cardiac muscle rejuvenesce, have good reputation extremely in international academia.
2007, anversa begins to head laboratory of medicine of second birth of hospital of woman of Mu of the case in cloth. He published 55 papers at least in this orgnaization. Before the researcher ever was described, this lab is enveloped to be in a kind of insecurity and anxious atmosphere. "Come 10 years, his whats are in charge of. " Jeffery Molkentin of children institute researcher says Xinxinnadi.
However, when all sorts of research groups try to reproduce these results, they failed. Nevertheless, the heart that a few scientists still try to be damaged C-kit infuse, the result is fond of care half.
Existence is con
Then, the sound of doubt appears in succession. Be in early 2004, 3 independence study panel report says they cannot duplicate the mouse experiment of Anversa.
Because data makes a holiday, anversa was published in 2012 " circularly " a paper of the magazine is removed to stalk of grain. Of the same age, " willow leaf knife " also make a statement, build a holiday to express to Anversa paper " care " .
At that time, the rate that the cell that Swedish researcher estimates human body 25 years old replaces every year is about 1% , and 75 years old fall to 0.45% . But Anversa and its work in the same placing are right in this paper and other paper these estimation raised doubt, they claim this kind is updated it is to 40 years old in 20 years old annual 7% , and rate rises as the growth of the age, 80 years old of crowds are as high as 19% .
Swedish group hopes to make clear why to study result photograph goes very far, but study in two constituent enjoyed data hind, swedish group suspects the example of Anversa got pollute, expressed to be anxious to means of its data processing.
Darrel Francis of British cardiology home is written article is straight point to, home of a few cardiology is met " adjust " data succeeds with proving his experiment was obtained.
College of medicine of haing Buddha university and hospital of woman of Mu of the case in cloth start investigation, confirmed Anversa distorts data, " circularly " the magazine agrees with cancel paper.
Anversa ever still corrected 8 papers, among them a lot of because fail to exposure interest conflicts and suffer doubt,be.
2015, anversa leaves Buligemu woman hospital, but relevant investigation did not stop, caused the attention of American government sector even, because he was chaired a lot of the project that funds by federal funds, drag in amount is huge.
2017, NIH sues Anversa and colleague to use con method diddle funds, hospital of woman of Mu of the case in cloth agrees finally to be reached with American government reconcile agreement, compensate for 10 million dollar.
Present setting of heart cardiogram abstraction with human 3d
The person such as Anversa sues a hospital however, say its investigate interior be related announce to give " circularly " editorial office, damaged their professional foreground thereby. Anversa denies him to be put in any academic dishonourable behavior, shift responsibility already recalled the first author of the paper.
Still not be clear about at present, college of medicine of haing Buddha university and hospital of woman of Mu of the case in cloth recall the appeal of the paper, the compromise that whether reachs with the government together is concerned. These two orgnaizations just allege, investigation decides 31 papers existence falsifies data, had informed all and relevant periodical, have policy of strict according to and code handling.
Assume office to did not publish any comments at the Anversa of university of Su Li world at present.
Can stop
"The cell did not do in the heart, do not try to announce these results. " Molkentin says.
The academic dishonourable of Anversa, of the influence is oneself and hospital of woman of Mu of the case in cloth not just, involve whole and relevant field even.
Domestic Charles Murry mentions pathology of Washington university heart and vessels, a few groups use dry cell to treat heart disease in against time research, each investigator want to reduce anguish for the patient not only, still want to become the person that creates the history.
And, still a few researcher continues to publish the research result that agrees with Anversa. Molkentin hope, remove draft this to be able to make people sober come down, stop to just go ahead to the mistake.
Harlan Krumholz of Yale cardiology home also expresses, "Look in me, of clearly is need vitrification. " scientific group needs to knew what to discover, why the paper is recalled, and the proposal that studies way about this domain.
Although periodical often according to scientific research orgnaization recall the proposal takes action, but also be not always is such, and need time sometimes. According to statistic, periodical publishs 3 million papers every year in all, recall about 1400.
The person's heart and heart container
" willow leaf knife " magazine spokesman Seil Collins says, after the proposal that receives haing Buddha university, anversa had been affixed in the paper that published 2011 attention label.
If 31 papers of Anversa are recalled entirely, will make he is in " the observation that remove draft " before the rank on the website enters the whole world very quickly 20. Current, remove before 10 scholars with most draft, each at least cancel 39 papers, those who rank the first place is Japanese anaesthesia grand of be apt to of investigator cane well, share 183 papers to be removed.
In recent years, cellular biology domain removes hair of draft incident frequency. Institute of Japanese manage chemistry is small Baofangqingzi says to excogitate " all-purpose cell " , be thought likelihood open up a brand-new research direction. But final investigation discovers this achievement exists " concoctive " and " distort " , relevant paper is removed to stalk of grain.
Tokyo university maintains biology of cell of element of institute of biology of cell of this officer member, Japan get military content to cross the person such as Bian Jiadian to be published in " science " and " nature " 5 papers that wait for a journal to go up exist learning, among them 1 by cancel.
" Chinese science signs up for " (2018-10-18 important news of the 1st edition)
