Research of a new medicine discovers American northwest university, inflammation includes arthritis, 1 model diabetic etc, it is to cause the prime cause with oneself disorder immunity. Inflammation produces the effect that expect is less than to function of human body biological clock, the likelihood brings about Morpheus and biological clock disorder.
This research uses a kind to call " gene switch " new technology, turning to gene is opened in small mouse model and shut inflammation. When researcher shuts inflammation switch, mice cannot judge time, the rest that also cannot keep complete is periodic.
Consider to discover, existence is associated between the origin of inflammation and control of human body biological clock.
If the body suffers from inflammation, can experience a kind of transition that the name is NF-kappa Beta(NFKB) genetic factor. NFKB is the activator of a series of chain-reacting or way, these react or the way brings about the ache of patient of inflammation sex disease and organization to destroy.
"NFKB also is join inflammation ' static breath - activity ' the key of mode " . Investigator says, when ache of human body muscle, take Buluofen to relieve inflammation, it is actually activation in what try to reduce inflammation.
Moreover, the connection between human body biological clock and immune system, to us understanding inflammation and infection sex disease have very great help.
The white blood cell that human body has a kind of key (call huge bite cell) , when contacting a bacterium, make the biological clock inside huge bite cell stops, let its agnail thereby.
When the body affects inflammation, the biological clock in huge bite cell can be shut. Put when very long period of time when inflammation, stop as biological clock, actually the likelihood makes a disease exasperate, normally chronic illness (be like kind of rheumatism arthritis) the patient is such.
Investigator says, since very long period of time, immune system and biological clock are mutual correlation, system of human body immunity produces different reaction to the bacterium.
Elaborate human body biological clock the action in immune system, provided new method for comprehensive treatment.
For example, biological clock function restores when treating inflammation disease, can help us understand the hair of inflammation to give birth to a mechanism.
Investigator expresses, the interaction between inflammation and biological clock, how to affect Morpheus with inflammation not only - arousal cycle is concerned, still concern with the working mechanism of immune cell and adipose cell.
This also studies the reason of inflammation is in just about.
