As the growth of the age, the mankind each systems will appear inevitably anile, reproductive system nature also is such, especially reproductive system of the female. Relevant data shows the female's infecund probability: 20-24 year old about 5.7% , 25-29 year old about 9.3% , 30-34 year old about 15.5% , 35-39 year old about 29.6% , 40-44 year old about 63.5% , the woman of 87% contracts infecund disease after 44 years old.
Normally for, 23 years old come 30 years old is the gold period of time of female fecundity, after exceeding this age, the female's fecundity begins to drop, it is especially after 35 years old, oocyte quality of the female and amount drop significantly, ovarian reserve function, embryonic bed rate and clinical and gravid rate all appear reduce; And genetic and unusual embryo and fetal occurence rate and abortive rate elevatory.
Problem of Yo of because crowd of this advanced age is medium prepotent actor more remarkable, a lot of senile women can seek the help of auxiliary reproduction technology. Assure basically the oocyte that acquires high quality however is success of auxiliary reproduction technology, ending of technology of because this age is right also auxiliary reproduction is put in very big impact.
One, ovarian reserve capacity and age
Ovarian reserve points to the primitive and follicular amount of the existence in ovarian organization, it is a when measure female fecundity main index, as the growth of the age, amount of the rest ovum will be less and less, ovarian reserve also is met less and less. Additional, ovarian reactivity is to point to ovarian inside follicular internally or outside the respondent ability that level of source sex hormone alters, it is to assure ovum development, mature, oviposit and the premise condition that enough ovum amount and high quality ovum obtain when having test tube baby. Clinical observation makes clear as a result, ovarian reserve capacity and ovarian reactivity all related to age height, namely the growth as the age, ovarian reserve capacity and ovarian reactivity all drop gradually.
2, uterine core condition and age
The stability of uterine core condition is the requirement that promotes embryonic growth, it is normal to include look of the film inside the uterus to get pitch of gender, uterus configuration and proper uterine tension. Look of the film inside the uterus suffers a gender to basically suffer inside the uterus structure of velar ply, organization and blood stream influence. Increase along with the age, the film inside the uterus all produces a series of changes on configuration and function, include collagen content to increase, inside female, progestational hormone suffers body to decrease in velar cell, produce exuviate film to change inside velar cubage and quantity of uterine blood stream decrease etc. And this a series of it is difficult that the change gave embryonic bed, development to cause huge.
3, embryonic quality and age
Reproductive cell of the female is born to be meant move toward consenescence gradually, the oocyte of 20 years old of young woman eduction of the left and right sides is only 2-3% happening chromosome is unusual, and when arriving 40 years old, this kind of risk is added to 30-35% . The age raised oocyte first time and rate of error of the 2nd meiosis happening. The addition with the fall of ovum quality and unusual chromosome behaves the stunt that is the embryo before cultivating and backwater, possibility of low or fetal deformation increases occurrence intelligence, pregnant metaphase abortion leads apparent heighten.
Say so, the age is very old to fecundity influence of the female, no matter be natural conception or test tube baby, choosing optimal age to undertake birth is the most scientific. Cannot no matter,blind thinks age size, test tube baby can succeed, data of statistic of domestic and international big sample book makes clear, the rate adopting baby that 45 years old of above make tube is extremely low, do not exceed 2% commonly, center of a lot of reproduction is so right the patient of 45 years old of above does test tube baby no longer.
From on the other hand for, oneself of pregnancy of senile lying-in woman and fetal risk increase, the odds with high disease of puerpera happening pregnant, diabetic gestation increases greatly, difficult labor, slink possibility also can rise, for the angle from the child, the occurrence transmissibility disease, probability that shuts disease oneself also can increase somewhat, the occurence rate of additionally a few congenital diseases increases somewhat. Because this of the right age is borne also most the body that is helpful for female oneself restores and realize prepotent actor Yo.
This shows, much old age can not do test tube baby. The treatment of test tube baby has in appropriate age, the successful rate that transplants not only is higher, and can reduce pregnancy complication, obtain more healthy offspring.
