Recently, come from Canadian wheat to overcome family of Farncombe of Mass spy university to digest the scientists of healthy institute to discover, alvine path bacterium may be mixed in angst of depressed disease in causing a process, having main effect.
This new research, will be published on July 28 " Nature Communications " , discuss alvine path bacterium first group the effect that the behavior change that causes to inchoate life pressure has.
Article newsletter writer, wheat overcomes Premysl Bercik of associate professor of medicine of college of medicine of Mass spy university to point out: "The small rat that we are in to already was built first makes clear in angst and depressed model, bacterium to revulsive this kind of deviant behavior, had crucial effect. But it is a bacterium not only, suffer the host that should stimulate however (small rat endured inchoate life to should be stimulated) reach its are microbial between two-way communicate, brought about angst and depressed. Brought about angst and depressed..
Our early knows, alvine path bacterium may affect behaviour, but what the most research previously uses is health, normal small rat. Read related: Does meeting palm control alvine path bacterium our thought? .
In this research, researcher passes course of depart of baby of a kind of mother, make small rat endures life inchoate should stimulate, mean, from 3 arrive 21 days, new student small rat departs with their mother everyday 3 hours, kiss their replace mother next beside.
Above all, bercik and his group confirms, have complex microbial convention small rat, experienced depart of the mother's body, showed angst and depressed appearance behaviour, should stimulate hormone the level of coriaceous alcohol appears unusual. Release as what main nerve gives qualitative acetyl choline, these small rat also show obstacle of alvine line function.
Next, researcher repeats same test below aseptic condition, when discovery lacks a bacterium, the small rat with separate the mother's body still has a change should stimulate hormone level and obstacle of alvine line function, but their bearing is similar to contrast group of small rat, did not show any angst or depressed sign.
Next, they discover, when the asepsis with separate the mother's body small rat infection comes from contrast when the bacterium of small rat, bacterial composition and metabolization active are in a few change produced inside week, small rat begins to show angst and depressed.
Bercik says: "However, if we will stimulate the bacterium of small rat oneself, move arrives be not the asepsis that should stimulate inside small mouse system, we did not observe unusual. This makes clear, in this model, host and microbial element, it is angst and place of development of depressed appearance behavior are indispensible. New student should stimulate can bring about should stimulate reaction to increase to with bowel functional obstacle, bacterium of path of bowel of this meeting change group, conversely, this can change the function of cerebrum again. This can change the function of cerebrum again..
He expresses: "According to this new research, we begin to explain alvine path is microbial with host between interaction and kinetic complex mechanism. Our data makes clear, new student should wash revulsive mushroom group distributing or the relatively minor change of its metabolization active, produce far-reaching effect possibly to grown host behavior. Produce far-reaching effect possibly to grown host behavior..
Bercik says, this is to march toward " understanding is microbial how to affect host behaviour " another pace, and the likelihood will observe the result is outspread formerly arrive mental disease domain. He says: "Decide whether this also applies to the mankind, will be very important. For instance, whether are we sending patient of sexual spirit disease formerly (if angst is mixed depressed) in detect an unusual bacterium group distributing, and different microbial metabolization is active. And different microbial metabolization is active..
