This is to was published in last year " Science " result of a research, this main research target that studies a group is acid of odd nucleotide of smoke acyl amine (NMN) , body internal energy promotes the synthesis of NAD+ . Body of natural condition servent puts the metabolization content NAD+ that be in in every cell, the protein that research discovers to NAD+ is controlling DNA rehabilitate - there is important role in protein interaction.
As the growth of the age pH indicator of the NAD+ inside body drops bring about capability of pair of wrong DNA repair to drop, DNA injury is accumulated. Experimental rat passes acid of odd nucleotide of amine of compensatory smoke acyl (NMN) the level that can raise NAD+ , rapid changeover this process, reach the goal that prevents cancer, radiate and ageing thereby.
The photograph is more anile than saying to fight truly, exacter wording should be to should consider to announce the physiology of a biochemistry in anile process changes, and discover odd nucleotide of smoke acyl amine is acerbity (NMN) can repair changes this, discovered an anile target is nodded namely. But: Consenescence is the physiology biochemistry process of many sided of a systematization, cause the consenescence of the sex of organic sex cell of many administrative levels, have more in biochemical element level change by tens of thousands, these change cannot say is attributed to an element to cause.
NMN had been considered to make actually old, be in early the research that Professor David Sinclair published 2013 makes clear, short-term to be taken orally uses acid of odd nucleotide of smoke acyl amine (NMN) can increase NAD+ , and changeover a lot of anile respects, improved their healthy condition greatly.
This research group was in March this year " Cell " also discover odd nucleotide of amine of the acyl that use tobacco is acerbity (NMN) have treatment to small rat, discover odd nucleotide of smoke acyl amine is acerbity (NMN) can activation fight consenescence enzymatic -- go acetyl is changed enzymatic (SIRT1-SIRT7) the advantage that will achieve imitate motion and dietary restriction. Increased the hematic flow of big rat, endurance and blood capillary density, achieve increase the result that take exercise, the blood that improves organ and organization flows. Because of the growth as the age, blood capillary density decreases with what blood flows is the main reason that causes mortality and incidence of a disease.
Those who deserve attention is, professor David Sinclair was fighting He Baili of anile enzymatic SIRT1 2003 connection was established between Lu Chunzhi, alcohol of white black false bellebore is the element of a kind of natural presence, in red wine in minim exists. Alcohol of white black false bellebore activations only SIRT1, odd nucleotide of smoke acyl amine is acerbity (NMN) can activation all go 7 times acetyl is changed enzymatic, SIRT1-7, consequently he thinks NMN is met bigger to health and life generation impact. The human body experiment of NMN therapeutics will be in hospital of Bostonian woman of cloth Lai root to begin to undertake this year.
